NAD+ Therapy — IV Infusion vs IM Injection.
Which Is Right for You?
By Lynn Adami BSN RN-BC — New Skin by Lynn, San Mateo
If you have been researching wellness treatments lately you have almost certainly encountered NAD+. It appears across longevity medicine, biohacking communities, aesthetic wellness practices, and mainstream health media with increasing frequency — and for good reason. NAD+ is one of the most clinically supported wellness interventions available today. At New Skin by Lynn in San Mateo, Lynn Adami BSN RN-BC offers NAD+ therapy in two distinct delivery formats — intravenous infusion and intramuscular injection — each with its own clinical profile, time commitment, and ideal client profile.
WHAT IS NAD+?
NAD+ stands for Nicotinamide Adenine Dinucleotide — a coenzyme found in every cell of the human body that plays a central role in cellular energy production, DNA repair, and the regulation of biological processes associated with aging. Without adequate NAD+ levels cells cannot efficiently produce the energy they need to function — and the effects of that deficit are felt across multiple body systems simultaneously.
NAD+ levels naturally and significantly decline with age — research suggests levels drop by approximately 50% between the ages of 40 and 60. This decline is associated with reduced energy, cognitive fog, slower cellular repair, reduced stress resilience, and accelerated visible aging. Restoring NAD+ levels through therapeutic supplementation — whether intravenous or intramuscular — addresses this deficit directly at the cellular level.
NAD+ IV INFUSION — WHAT IT IS AND WHO IT IS FOR
Intravenous NAD+ infusion delivers the coenzyme directly into the bloodstream through an IV line — bypassing the digestive system entirely and achieving 100% bioavailability. This means the full dose reaches systemic circulation immediately and is available to cells throughout the body without any absorption loss.
At New Skin by Lynn NAD+ IV infusion is offered as part of the comprehensive IV infusion therapy menu — administered by Lynn Adami BSN RN-BC under physician medical direction as required by California law.
IV NAD+ is particularly well suited for:
-
Clients seeking intensive cellular restoration — particularly following periods of significant stress, illness, or burnout
-
Clients with more pronounced fatigue, cognitive fog, or energy deficits who want to feel a meaningful shift
-
Clients who want the most comprehensive NAD+ experience — full systemic delivery with immediate availability to all cells
-
Clients who can commit to a 60-90 minute session — IV infusion requires time for the drip to complete
-
Clients beginning a NAD+ protocol for the first time who want to establish a strong cellular baseline
One important note — NAD+ IV infusion is typically administered more slowly than other IV formulations because rapid infusion can cause temporary discomfort including chest tightness, nausea, or flushing. Lynn manages infusion rate carefully to ensure client comfort throughout the session.
NAD+ IM INJECTION — WHAT IT IS AND WHO IT IS FOR
Intramuscular NAD+ injection delivers the coenzyme directly into the muscle tissue — from where it is absorbed into the bloodstream over a short period. At New Skin by Lynn the NAD+ Youth Boost IM injection is available in two doses — 50mg and 100mg — making it highly flexible for different client needs and protocols.
IM injection is the more accessible and time-efficient delivery format — sessions take just minutes with no IV line, no extended chair time, and no downtime. Most clients return to normal activities immediately.
NAD+ IM injection is particularly well suited for:
-
Clients maintaining a regular NAD+ wellness protocol between IV sessions
-
Clients with busy schedules who cannot commit to a 60-90 minute IV session
-
Clients new to NAD+ who want to assess their individual response before committing to IV infusion
-
Clients seeking consistent low-level NAD+ support as part of a broader wellness routine
-
Clients who experienced discomfort during IV NAD+ infusion and prefer a more comfortable delivery method
Lynn recommends starting with the 50mg IM dose for first-time NAD+ clients — assessing individual response before progressing to 100mg or IV delivery.
HOW DO THE TWO FORMATS COMPARE?
Bioavailability — IV infusion delivers 100% of the dose directly into the bloodstream with immediate systemic availability. IM injection delivers a slightly lower effective dose due to the absorption process from muscle tissue — but still achieves meaningful systemic levels.
Speed of effect — IV infusion produces faster and more pronounced systemic effects — many clients report feeling a notable shift in energy and mental clarity during or immediately after the session. IM injection produces more gradual effects that develop over hours to days.
Session time — IV infusion requires 60-90 minutes. IM injection takes approximately 5-10 minutes.
Comfort — IV infusion requires a cannula and extended chair time. Rapid infusion can cause temporary discomfort. IM injection involves a single injection — similar to a standard wellness shot — with minimal discomfort.
Cost — IV infusion is priced higher than IM injection reflecting the additional time, materials, and clinical monitoring involved.
Frequency — IV infusion is typically administered monthly or as needed for intensive support. IM injection can be administered weekly or bi-weekly as part of a regular wellness protocol.
WHAT RESULTS CAN CLIENTS EXPECT?
Both delivery formats support the same fundamental goals — restoring NAD+ levels to support cellular energy production, cognitive function, DNA repair, and the biological processes associated with healthy aging. The difference is in the intensity and immediacy of effect rather than the underlying mechanism.
Most clients notice improved energy, mental clarity, mood, and stress resilience following NAD+ therapy — with effects developing over days to weeks following IM injection and more immediately following IV infusion. Consistent sessions as part of a regular wellness protocol deliver the most meaningful and sustained results — NAD+ therapy is most effective when maintained over time rather than administered as a one-time intervention.
SKIN HEALTH AND NAD+
From a skin perspective NAD+ supports cellular repair processes that directly influence skin quality. Cellular energy is required for collagen synthesis, skin barrier maintenance, and the natural cell turnover that keeps skin looking fresh and vital. Declining NAD+ levels contribute to the visible signs of skin aging — dullness, loss of firmness, and slower recovery from environmental damage.
Clients who include NAD+ therapy as part of their regular wellness protocol at New Skin by Lynn frequently report improvements in overall skin quality that complement their aesthetic treatments — a natural synergy between the wellness and skin care dimensions of the practice.
LYNN'S CLINICAL PERSPECTIVE
"NAD+ therapy is one of the most genuinely exciting areas of wellness medicine right now — the science behind it is robust and the clinical results I see in clients are consistent and meaningful. I typically recommend starting with the 50mg IM injection to assess individual response — it gives clients a clear sense of how their body responds to NAD+ before committing to IV infusion. For clients who are experiencing significant fatigue or cognitive fog the IV infusion is a more powerful starting point. The right format depends entirely on what the client is trying to achieve and what fits their lifestyle — which is exactly why we discuss it in detail during the consultation." — Lynn Adami BSN RN-BC, New Skin by Lynn
BOOK A CONSULTATION
Interested in NAD+ therapy at New Skin by Lynn? Book a complimentary consultation with Lynn to discuss which delivery format is most appropriate for your wellness goals.
New Skin by Lynn is located at 241 S San Mateo Dr, Ste 7, San Mateo, CA 94401 — serving clients from Burlingame, Hillsborough, Redwood City, and throughout the San Francisco Bay Area.
Phone or Text: 650-484-4404